Discover a Faster Path to Diagnosis
No more waiting weeks for inconclusive results. Rapid On-Site Evaluation (ROSE) delivers immediate answers to your clinicians, so you can begin focusing on what matters – getting better.
The ROSE Difference
A single biopsy that delivers a conclusive result can save you weeks of uncertainty. It may even save your life.
By incorporating Rapid On-Site Evaluation (ROSE), healthcare providers ensure patients receive immediate sample validation, lowering false negatives (failing to detect cancer despite its presence) and easing anxiety. With every step, ROSE accelerates your path to a clear and accurate diagnosis and timely treatment. Ask your doctor if ROSE is part of your biopsy plan. Your peace of mind and health depend on it.
Introduction: Why ROSE?
“The ROSE procedure has become the standard for FNA lung procedures. Every hospital should be able to perform ROSE.”
Real Time Assessment
ROSE allows a trained specialist to examine your biopsy sample as it’s being taken.
Immediate Feedback
If the sample isn’t adequate, the medical team can immediately collect more tissue, reducing the chance you’ll need a second biopsy.
Less Anxiety, Faster Peace of Mind
According to research, ROSE lowers stress and helps you and your healthcare team move forward with a clear and accurate diagnosis.
How ROSE Works
1. Biopsy Begins
A thin needle extracts a small sample of tissue cells from the suspicious lump or mass (Fine Needle Aspiration, or FNA).
Why FNA? It’s minimally invasive with fewer complications than surgical biopsies.
2. Immediate Slide Prep
The sample is placed on a slide or in an ASP Vial for on‑site staining and evaluation. (ROSE Prep™ pro that can do this in 70 seconds.)
3. On Site Expert Review
A trained specialist examines the slide on-site using a microscope or via remote viewing system.
AI Enhancements: Some facilities use advanced software such as ROSE Assist™ to highlight suspicious cells faster.
4. Rapid, Real Time Confirmation
If more tissue sample is needed, doctors collect the cells immediately, eliminating the need for a return hospital visit.
If the sample is deemed adequate, they finalize the procedure—no repeat biopsy required in most cases.
5. Preliminary Diagnosis
Typically, you’ll know whether the sample appears benign or suspicious by the end of the procedure. This dramatically shortens your wait for a detailed final diagnosis.
Patient Impact: Research & Real-World Evidence
Proof That ROSE Helps Patients. Based on extensive research, here’s what patients experience with ROSE:
25%
Reduction
in Anxiety
Patients undergoing a lung biopsy with ROSE felt significantly less stressed, thanks to fewer “what if?” moments (Wang et al. Japanese Journal of Clinical Oncology, 2019).
17%
Reduction
in Sedation
With fewer needle passes needed (3.1 vs. 4.0), sedation demands drop, particularly helpful for patients with other health conditions (Xu et al. Technology in Cancer Research & Treatment, 2020).
30%
Reduction
in Repeat Procedures
For certain diseases and suspicious pulmonary nodules, real-time assurance of sample adequacy means fewer repeated bronchoscopies (Min Li et al. Frontiers in Medicine, 2022).
12 Point
Increase
in Patient Satisfaction
Patients whose biopsies included ROSE rated their experience noticeably higher, citing greater comfort and overall satisfaction (AbdelDayem et al. QJM: An International Journal of Medicine, 2024).
Confidence in Care
Knowing your biopsy was confirmed on the spot means greater confidence in your diagnosis and trust when adhering to follow-up treatment plans (Bandiera et al. International Agency for Research on Cancer, 2020).
ROSE enables a 15-25% increase in accurate diagnoses for certain cancers, such as lung and pancreatic.
Because Every Day Counts:
How Speed Impacts Your Cancer Care
Every extra week of waiting for a second biopsy or further tests can open the door for tumor growth, especially in rapidly progressing cancers.
Time Sensitive Tumor Growth
Small cell lung cancer (SCLC) can double in size in as little as 20–50 days. Aggressive non-small cell lung cancers (NSCLC) risk significant progression, with 10% exhibiting doubling times in just 2–4 weeks (Travis et al. WHO Classification of Tumors of the Lung, 2021).
Escalating Stage
Studies reveal that each additional month before a definitive diagnosis increases the probability that the cancer will be found at a more advanced stage (Neal et al. British Journal of Cancer, 2015).
Delays in Cancer Diagnosis
Without ROSE, an “insufficient sample” report can force you to book and wait for a second biopsy, typically adding another 30‑60 days to the diagnostic timeline and giving fast‑growing tumors much more time to advance (Jackman et al. Journal of Clinical Oncology, 2005).
Repeat Biopsies Mean More Waiting
Conventional approaches might require multiple appointments if the initial sample is insufficient, forcing you into repeated doses of sedation and out of your normal life.
Frequently Asked Questions About ROSE
Is ROSE covered by insurance?
Many insurance plans cover ROSE, recognizing that it prevents repeat procedures. Always confirm coverage with your provider.
How does ROSE compare to a standard biopsy?
ROSE does not replace a standard biopsy; it enhances it by verifying sample adequacy in real time, thus lowering the risk of inconclusive results.
Does ROSE add extra time to my procedure?
Typically, it adds only a few minutes for on‑site review, which is far less than the weeks you’d spend waiting on a repeat biopsy.
Can I request ROSE at any hospital?
Not all hospitals offer ROSE. Ask your doctor or call the facility to see if they have cytopathologists or telepathology specialists available to use ROSE.
Does ROSE ensure a definite diagnosis immediately?
ROSE provides preliminary on‑site feedback on the tissue sample. A final, detailed pathology report still takes some time, but ROSE greatly reduces the chance of insufficient material and an inconclusive biopsy.
How does ROSE Improve Time to Treatment?
Fewer Repeat Procedures: Real-time verification significantly lowers rates of inconclusive results, enabling you to move from “possible cancer” to a definitive diagnosis more quickly (Liang et al. Frontiers in Medicine, 2022).
Accelerated Path to Therapy: Starting the right treatment early can be especially critical in aggressive cancers like non-small cell lung cancer, in which a delay of 2–4 weeks can cut median survival by the years (Slotman et al. Journal of Thoracic Oncology, 2015).
Your Next Step: Ask For ROSE
Empower yourself: Patients who ask for ROSE often help their care team remember the value of real-time sample checks. If your facility doesn’t currently offer ROSE, voice your interest. It’s your right to seek the most effective, patient friendly approach. You also can look for a facility that does offer ROSE.
Reminder: Fewer repeat biopsies mean less waiting, less sedation, and less worry – allowing you to focus on healing rather than scheduling yet another procedure.
Learn More / Additional Resources
MEAGAN’S STORY: Hear how others have benefited from a one time biopsy experience thanks to ROSE.
CONTACT US: Have questions about how ROSE can help you? Reach out—we’re here to guide you.
